What are psychedelics and dissociative drugs?  lead image

What are psychedelics and dissociative drugs?

While the effects of psychedelics and dissociatives can be fascinating, it's important to approach them with caution.
Sunday, October 29, 2023

Psychedelics and dissociatives – let's dive into the world of mind-altering substances and explore their effects, risks, and potential therapeutic uses. These substances can temporarily shake up your mood, thoughts, and perceptions of reality, creating an intense and exhilarating experience for your mind.

Psychedelic drugs primarily work by influencing the way your brain processes serotonin, a chemical that plays a crucial role in regulating mood. Familiar names in this realm include psilocybin, LSD, DMT, mescaline, and NBOMes. They enhance your senses, making visions vivid and introspective, amplifying your emotions and creating a sense of connectedness. Imagine your brain throwing the coolest party ever, full of profound insights and mind-boggling experiences.

On the other hand, dissociative drugs, such as ketamine and PCP, alter the processing of glutamate, another chemical in the brain. These substances can transport you to a whole new dimension, where you may feel disconnected from your body and environment. It's like floating on a cloud, offering a sense of detachment and otherworldly experiences.

Furthermore, there are some substances, like MDMA, ibogaine, and salvia, that possess both psychedelic and dissociative effects. These compounds have a unique ability to create a double whammy of trippiness. They can bring you heightened sensory experiences, feelings of euphoria, and an altered perception of time and space.

While the effects of psychedelics and dissociatives can be fascinating, it's important to approach them with caution. These substances can have unpredictable effects on individuals, and the experience can vary greatly from person to person. It's crucial to be mindful of set and setting, meaning your mindset and the environment in which you choose to explore these substances.

There are also potential risks associated with psychedelic and dissociative drug use. The intensity of the experience can sometimes lead to anxiety, fear, and confusion. It's important to have a trusted and responsible trip sitter—a friend who remains sober—to ensure your safety and well-being. Additionally, the use of these substances may have legal repercussions depending on your location.

Furthermore, it's important to note that these substances are not without their potential benefits. In recent years, there has been growing interest in the therapeutic potential of psychedelics and dissociatives. Research suggests that they may have a positive impact on mental health conditions such as depression, anxiety, and post-traumatic stress disorder (PTSD). However, it's crucial to seek guidance from trained professionals if considering these substances for therapeutic purposes.

So, if you're looking for an eye-opening experience, a chance to explore the depths of your mind, or simply a journey into trippiness, psychedelics and dissociatives offer just that. Just remember to approach them responsibly, be aware of the risks, and if considering therapeutic use, seek guidance from professionals in the field. Embrace the wonders, let your mind soar, and enjoy the colourful world of psychedelics and dissociatives with a big, cheerful grin on your face. Let's get trippy!

Psychedelic drugs

Psychedelic drugs, including psilocybin, LSD, DMT, mescaline, and NBOMes, are substances known for their ability to induce profound alterations in perception, cognition, and consciousness. These substances are often referred to as "psychedelics" due to their mind-expanding and consciousness-altering effects.

Psilocybin is the active compound found in "magic mushrooms," which are fungi that have been used for centuries in cultural and spiritual practices. When consumed, psilocybin is converted into psilocin, which activates serotonin receptors in the brain and leads to altered perception, enhanced sensory experiences, and changes in mood and cognition.

LSD, or lysergic acid diethylamide, is a synthetic compound that was first synthesized in the 1930s. It is known for its potent psychedelic effects, producing alterations in perception, hallucinations, and an expanded sense of consciousness. LSD interacts with serotonin receptors in the brain, leading to its unique psychoactive effects.

DMT, or dimethyltryptamine, is a naturally occurring compound found in various plants and animals. DMT is also produced endogenously in the human body, especially during heightened states of consciousness, such as dreaming and near-death experiences. When consumed, DMT can induce intense hallucinations, out-of-body experiences, and deep spiritual insights.

Mescaline is the primary psychoactive compound found in the Peyote cactus and some other cacti species. When ingested, mescaline induces psychedelic effects such as altered perception, visual and auditory hallucinations, and spiritual experiences. It interacts with serotonin receptors, primarily the 5-HT2A receptor.

NBOMes, or N-Benzylmethoxy substituted phenethylamines, are a group of synthetic substances that have a similar chemical structure to LSD but possess their unique effects. They were initially developed as research chemicals but have been encountered in illicit drug markets. NBOMes can produce visual distortions, hallucinations, and euphoria, but they also pose significant health risks and have been associated with adverse events and fatalities.

What classifies these substances as psychedelic drugs is their ability to induce profound changes in perception, including visual and auditory hallucinations, alterations in time perception, synesthesia (blending of senses), and enhanced introspection. These drugs often stimulate serotonin receptors in the brain, particularly the 5-HT2A receptor, leading to these mind-altering experiences.

It is important to note that the use of these substances comes with potential risks, including psychological distress, anxiety, and the potential for triggering or exacerbating mental health conditions, especially in vulnerable individuals. It is crucial to approach the use of these substances responsibly, in safe environments, and with proper knowledge.

Dissociative drugs

Ketamine, nitrous oxide, and PCP are all considered dissociative drugs. 

Ketamine: Ketamine is a medication that was initially developed as an anesthetic and is commonly used in veterinary medicine. As a dissociative drug, it works by blocking certain brain receptors, particularly those involved in the transmission of the neurotransmitter glutamate. This disruption in the brain's communication pathways leads to dissociation, where individuals may feel detached from their body, environment, or reality. Ketamine can induce hallucinations, altered perceptions, and a sense of floating or out-of-body experiences. It is also known for its pain relief properties and potential antidepressant effects. 

Nitrous oxide: Nitrous oxide, also known as laughing gas, is a colourless and odourless gas commonly used in dentistry and anesthesia. It is inhaled through a mask or a small canister. Nitrous oxide is a dissociative drug as it can cause a sense of detachment from oneself, resulting in euphoria, relaxation, and altered perceptions. It is particularly known for its giggly and lightheaded effects, hence the nickname "laughing gas." 

PCP (Phencyclidine): PCP is a synthetic drug that was originally developed as an anesthetic but later discontinued due to its side effects. As a dissociative drug, PCP affects the NMDA receptors in the brain, leading to dissociation from one's body and environment. It can induce a wide range of effects, including hallucinations, distorted perceptions of time and space, increased strength, and feelings of invulnerability. However, PCP is known to have a high potential for abuse and can cause severe side effects, including aggression, confusion, and delirium.

Dissociative drugs like ketamine, nitrous oxide, and PCP are called such because they create a dissociative state, where individuals may feel detached from their surroundings, their own body, or their sense of self. They can induce altered perceptions, hallucinations, and a sense of being disconnected from reality. This dissociation can potentially lead to a disconnection between thoughts, feelings, and behaviour.